siRNA

Our MISSION Predesigned siRNA and Pre-arrayed siRNA libraries are manufactured using the advanced Rosetta siRNA Design Algorithm, which significantly reduces off-target effects and ensures effective target gene knockdown. We offer both validated positive siRNA controls and validated negative siRNA controls to complement your siRNA experiments.

We offer complete custom services for siRNA synthesis including complex modifications, and many scale and purification levels. Additionally, we have a novel nanoparticle-based siRNA transfection reagent, N-TER, designed to allow effective delivery of siRNA into even traditionally difficult to transfect cell lines. 

We are proud to offer MISSION In Vivo Quality and iScale Oligos™ siRNA.  These superior quality molecules are suitable for RNAi research in animals, giving you the quantity of siRNA and high purity requirements necessary for successful in vivo experiments.  Our expertise in oligo manufacturing allows us to offer a variety of modifications and scales suitable for any stage in your in vivo research.

More information on Sigma’s siRNA products and how to place an order.


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