Our RNAi tools are supported by excellent service, systems, equipment and scientists to ensure your research is of the highest quality.
Sigma provides innovative RNAi products to suit your exact requirements. Custom synthesis and custom modifications are available for siRNA, including amine, biotin, Cy-dyes, fluorescein and phosphate labels. For in vivo applications, 2’OMe bases can be used to increase the serum stability of siRNA duplexes. All of our siRNA oligos undergo vigorous process monitoring and strict quality control.
For shRNA, we offer many custom services, including: custom cloning, sequencing, DNA preparation and lentiviral preparation, with options for vectors, selection and promoters. Our custom services also extend to large scale and high titer lentiviral particles, custom production of lentivirus using your clones, and custom gene family sets.