MISSION® RNAi

Your time is valuable, spend it on discovery!

We provide leading RNA interference (RNAi) tools for gene silencing (siRNA, shRNA, esiRNA, miRNA).  MISSION siRNA and esiRNA products offer effective target gene knockdown with reduced off-target effects, while our MISSION shRNA portfolio includes the highly-validated lentiviral-based shRNA libraries of The RNAi Consortium (TRC1/1.5 and TRC2).  MISSION miRNA mimics utilize a novel design proven to minimize off-target effects of the sense strand, allowing for accurate functional screens. From basic RNAi to advanced RNAi, the MISSION RNAi portfolio provides you with a comprehensive range of innovative products. Finding RNAi tools for your gene of interest is easy with our Your Favorite Gene search engine.

Screening often lies at the beginning of most discovery research.  The network of possible molecular interactions leading to the causal phenotype within a given system, pathway or disease is astounding.  It is essential to begin with the most validated and comprehensive RNAi screening tools available.  Discovering novel biological interactions leads to a host of characterization and validation studies.  To help you with your follow-up validation we offer a large variety of custom options and services.  Spend your time on discovery!

Upcoming events

AACR 2011

The 102nd AACR Annual Meeting 2011 will be an exciting program on the best and latest in cancer research, in which a wide swath of the cancer research ...

Location:
Orlando, FL

Dates:
2 – 6 April 2011

Experimental Biology 2011

Experimental Biology is an annual meeting comprising of nearly 13,000 scientists and exhibitors representing six sponsoring societies and 16 guest soc ...

Location:
Washington, DC

Dates:
9 – 13 April 2011

RNAi Europe

The conference will be co-located with qPCR Europe and Epigenetics Europe. Agenda topics will include target discovery and validation, delivery techni ...

Location:
Munich, DE

Dates:
8 – 9 September 2011

December 14, 2010 @ 11:48 pm by Sigma Aldrich
Scientific breakthrough by Sigma Advanced Genetic Engineering (SAGE™) Labs enables creation of more sophisticated models of human disease ...
August 9, 2010 @ 3:32 pm by Sigma Aldrich
St. Louis, MO. – August 9, 2010 – Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® ...
August 5, 2010 @ 7:47 am by Sigma Aldrich
Sigma® Life Science to Analyze Plasma Samples from Framingham Heart Study in Researching Novel Biomarkers for Cardiovascular Disease St. Lo ...
January 31, 2012 @ 4:00 pm
Scientists at the Max Planck Institute for Chemical Ecology, Germany, are now using a procedure which brings forward ecological research on insects: They study ...
January 11, 2012 @ 5:21 am by Sigma BioBlogs
Today we talk with Maven of Hip Hop, Adjunct Biology Professor, and Outreach Scientist, Danielle N. Lee. Dr. Lee is not your average biology professor, or “av ...
December 7, 2011 @ 6:21 am by Sigma BioBlogs
Congratulations to Dr. Gail M. Seigel on winning our Antibody Review Contest. To win the $500 American Express Gift Card, Dr. Seigel submitted a product review ...
November 21, 2011 @ 10:05 am by Sigma BioBlogs
Today we interview with Bora Zivkovic, Blog Editor at Scientific American, where he manages the coordination of blogs from Scientific American writers, and blog ...

Your favourite gene

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