MISSION® RNAi

Your time is valuable, spend it on discovery!

We provide leading RNA interference (RNAi) tools for gene silencing (siRNA, shRNA, esiRNA, miRNA).  MISSION siRNA and esiRNA products offer effective target gene knockdown with reduced off-target effects, while our MISSION shRNA portfolio includes the highly-validated lentiviral-based shRNA libraries of The RNAi Consortium (TRC1/1.5 and TRC2).  MISSION miRNA mimics utilize a novel design proven to minimize off-target effects of the sense strand, allowing for accurate functional screens. From basic RNAi to advanced RNAi, the MISSION RNAi portfolio provides you with a comprehensive range of innovative products. Finding RNAi tools for your gene of interest is easy with our Your Favorite Gene search engine.

Screening often lies at the beginning of most discovery research.  The network of possible molecular interactions leading to the causal phenotype within a given system, pathway or disease is astounding.  It is essential to begin with the most validated and comprehensive RNAi screening tools available.  Discovering novel biological interactions leads to a host of characterization and validation studies.  To help you with your follow-up validation we offer a large variety of custom options and services.  Spend your time on discovery!

Upcoming events

RNAi & miRNA Europe

The annual RNAi & miRNA Europe is Europe's largest conference & exhibition dedicated to RNA interference. This year event will take place in ...

Location:
Dublin, Ireland

Dates:
14 – 15 September 2010

Neuroscience 2010

Neuroscience 2010, the 40th annual meeting of the Society for Neuroscience, will take place between 13-17 in San Diego, California Scientists will con ...

Location:
San Diego, California, USA

Dates:
13 – 17 November 2010

August 9, 2010 @ 3:32 pm by Sigma Aldrich
St. Louis, MO. – August 9, 2010 – Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® ...
August 5, 2010 @ 7:47 am by Sigma Aldrich
Sigma® Life Science to Analyze Plasma Samples from Framingham Heart Study in Researching Novel Biomarkers for Cardiovascular Disease St. Lo ...
April 20, 2010 @ 9:19 am by Sigma Aldrich
Sigma-Aldrich® (NASDAQ: SIAL), today announced an extension to its award-winning CompoZr® product offering with the global release of the CompoZr Targeted Int ...
September 2, 2010 @ 7:00 pm
Melbourne, Sep 3, 2010 (ABN Newswire) - Benitec Limited (ASX:BLT) (PINK:BNIKF), a leading Australian based company specialising in RNA interference (RNAi) techn ...
September 2, 2010 @ 7:00 pm
This new product range combines Sigma’s proprietary CompoZr zinc finger nuclease (ZFN) technology with experience in gene silencing, to offer innovative ...
September 1, 2010 @ 7:00 pm
Melbourne, Sep 2, 2010 (ABN Newswire) - The Directors of Benitec Limited (ASX:BLT) (PINK:BNIKF) are pleased to provide this update on the progress of the patent ...
September 3, 2010 @ 4:18 pm by Sigma BioBlogs
AMPK AMPK AMPK!!!!  That’s all that Larry Shapiro’s lab at Columbia University in NYC can talk about in “Naturally Obsessed: The Making of a ...
August 27, 2010 @ 6:21 pm by Sigma BioBlogs
5 years.  Plasma from 7,000 participants.  180 potential biomarkers. Will it be enough to gain a greater understanding of the genetics and biological pathways ...
August 20, 2010 @ 5:04 pm by Sigma BioBlogs
One of our goals with the Your Favorite Gene tool is to create one place for as much information as possible about a specific gene or protein of interest. Here ...

Your favourite gene

Visit other Sigma Bio sites

Sign up for email updates

Follow us

See what other scientists are saying about Sigma Life Science right now on our social media pages: